Physiology in an air-polluted world
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We work with the Moosavi lab at Oxford Brookes University on cardio-, cerebrovascular and behavioural impact of cigarette and e-cigarette smoking, and with the Robbins lab at the University of Oxford on respiratory correlates of the same. We also collaborate with researchers at The University of Sheffield on the impact of carbon monoxide on cardiac development, with Simon Clarke (Aintree Hospital) on improving accuracy of CO measurements in exhaled gases, and with Dr Prachi Stafford at Sheffield Hallam University to develop techniques for looking at carbon monoxide impact in cell monolayers and tissues. Collaborations with colleagues in the Biomolecular Research Centre (BMRC) at Sheffield Hallam University are initiated on select smaller projects to use the above techniques in a range of experimental paradigms.

Current students

BSc and Erasmus students working on final year projects. Projects include investigating the impact of carbon monoxide on an avian model of development, developing an exposure chamber for carbon monoxide exposure of tissues and cells, analysing the impact of carbon monoxide on reaction time, autonomic control and cognitive processing, and studying the effect of carbon monoxide on markers of cerebrovascular disease in a population of smokers (the latter in collaboration with Oxford Brookes University).

Past PhD students

Emmanuel Debrah worked on cerebral mechanisms of breathlessness and its reliefs, with a particular focus on the role of the insula. He completed his PhD in Clinical Respiratory Physiology at Oxford Brookes University in 2016.

Anja Hayen worked on identifying brain mechanisms of dyspnoea in healthy volunteer models using functional magnetic resonance imaging. She completed her DPhil in Neuroscience at the University of Oxford in 2014. Anja now works as a senior scientist at P1Vital Ltd.